The paper presents two emblematic examples located at the extremes of the most significant phases of building industrialization in Italy. The first example, in Campania, is the Pozzi Ginori complex in Sparanise (1960-1963) by Luigi Figini and Gino Pollini; the second, in Lazio, is the IBM Italia factory in Santa Palomba (1979-1984) by Marco Zanuso. These industrial complexes both belonged to a program for the industrial development of the most disadvantaged socio-economic areas in Italy. These two industrial plants, resulting from studies by well-known designers, represent the transition from formal and technological experimentation to an adaptation to standard production. They involve the whole project and the construction site and are characterized by the concentration of various innovative aspects, such as the treatment of finishing materials and a sophisticated relationship between building typology and landscape context.